Custom Peptides
Genscript Corporation OVA Peptide (257-264)
This is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
Genelink Random Hexamers, 100 μg, 6 bases, 5'-d(NNNNNN)-3', Equimolar 25% A, C, G, T, ~54 nmol/molecule, HPLC purified
Random Hexamers (100 μg) from GENELINK are a versatile mixture of oligonucleotides, six bases in length, designed for a range of molecular biology applications. These primers are crucial for processes like DNA probe labeling, first-strand cDNA synthesis, and the detection of genetic variations. The random nature of the sequence allows for extensive coverage of target DNA or RNA templates, making them ideal for numerous genomic studies.
- Facilitates DNA probe labeling, cDNA synthesis, and RAPD analysis.
- Enables production of high specific activity labeled DNA probes for sensitive detection.
- Provides random initiation sites across varied RNA templates.
- Supports identification of genetic variations for genetic mapping.
Cayman Chemical pIodoClonIdInhydrochLRI 10mg
A partial agonist of the α2-adrenergic receptor, minimally inhibiting adenylate cyclase through this Gi protein-coupled receptor although it binds avidly (Ki = 1.0 nM); potentiates platelet aggregation by ADP (EC50 = 1.5 µM) and inhibits epinephrine-induced aggregation (IC50 = 5.1 µM)
Cayman Chemical SureLIghtPE-695 10mg
An atypical antipsychotic an agonist of 5-HT1A receptors (EC50 36.31 nM for inhibition of forskolin-induced adenylate cyclase activity in HeLa cells expressing human receptors) as well as an inverse agonist of 5-HT1D receptors (IC50 2.69 nM) and a partial agonist of 5-HT1B receptors (EC50 6.17 nM) in [35S]GTPYS binding assays an antagonist at 5-HT2A and dopamine D2 receptors (Kis 1.15 and 1.29 nM respectively) in cell-based assays inhibits d-amphetamine-induced hyperactivity and apomorphine-induced stereotypy in rats (ID50s 1.53 and 2.43 mg/kg respectively)
Cayman Chemical AzIdoIndolen 1 10mg
A synthetic CB structurally similar to UR-144, XLR11, and a number of other synthetic CBs with a hydrazide linking the tetramethylcyclopropyl group to the aminoalkylindole group; intended for forensic and research applications
Cayman Chemical SureLIghtAlophycocynInA 10mg
Immunogen Synthetic peptide from the C-terminal region of human nNOS Host Rabbit Cross Reactivity (−) eNOS and iNOS Species Reactivity ( ) Human and rat Applications ICC IHC and WB
Cayman Chemical EnrofloxacIn-d5 10mg
An internal standard for the quantification of enrofloxacin by GC- or LC-MS
Cayman Chemical BImIralIsIb 10mg
A pan inhibitor of PI3Ks and an inhibitor of mTOR (IC50s = 33, 661, 708, 451, and 89 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR, respectively); selective for these kinases over a panel of cell surface and nuclear receptors, membrane channels, transporters, kinases, proteases, and phosphodiesterases at a concentration of 10 μM; has anticancer activity (average GI50 = 0.7 μM across the NCI 60 human cancer cell line panel); reduces tumor growth in a dose-dependent manner in a PC3 prostate cancer mouse xenograft model
Cayman Chemical Desmethyl CarvedIlol 10mg
An active metabolite of carvedilol; inhibits store-overload-induced calcium release in HEK293 cells expressing RyR2R4496C (IC50 = 7.62 µM); reduces increases in heart rate and prevents decreases in diastolic blood pressure induced by isoproterenol in conscious rabbits (ED50s = 32 and 5 UG/kg)
Cayman Chemical 5- 3 4-DIhydroxyphenylV 10mg
An active metabolite of various polyphenols; an inhibitor of MMP-1 and MMP-2 collagen degradation activity (IC50s = 108 and 106 nM, respectively), MMP-1 and MMP-9 gelatin degradation activity (IC50s = 45.2 and 17.7 nM, respectively), and MMP-2 and MMP-9 elastin degradation activity (IC50s = 61.8 and 89 nM, respectively); scavenges free radicals in a TEAC assay
Cayman Chemical DSethoxy QuetIapInhydroch 10mg
An active metabolite of quetiapine; binds to dopamine D2 receptors (IC50 = 1,330 nM); reduces apomorphine-induced climbing in mice; reduces apomorphine-induced swimming deficits in mice
Cayman Chemical PPTNhydrochlorIde 10mg
A P2Y14 receptor antagonist; inhibits forskolin-induced cyclic AMP accumulation in C6 cells expressing human P2Y14 (EC50 = ~10 nM) but not CHO cells expressing P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 at 1 µM; inhibits UDP-glucose-induced IL-1β and CCL2 secretion, as well as ERK, JNK, and p38 MAPK phosphorylation in isolated rat SGCs at 5 µM; trigeminal administration reduces CFA-induced mechanical hyperalgesia in rats at 5 and 10 µM
Cayman Chemical 2Bromo4methylpropIophenon 10mg
An analytical reference standard categorized as a precursor in the synthesis of cathinones; intended for research and forensic applications
Cayman Chemical 1mthyl1 4dIhydronIcotInam 10mg
A nicotinamide derivative; inhibits β-elimination activity of hSR (IC50 = 177 μM)